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The key to controlling many of these issues is to identify them early and initiate a plan of complete and thorough treatment and relapse prevention. This syndrome is a result of poor nutrition and a lack of thiamine in the diet. Other research suggests that cannabis may have medicinal effects for a number of gastrointestinal disorders, such as irritable bowel syndrome, whereas other research suggests that it may be associated with these types of disorders in some individuals. Chronic users of cocaine suffer decreased appetite as a side effect of their cocaine use. As is always the case, individuals who suffer the physical effects of substance use disorders need to engage in some form of structured substance use disorder treatment program in addition to receiving any specialized treatment for their medical issues.

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Wernicke-Korsakoff syndrome is reversible if it is caught early in its progression; however, chronic alcoholics with long-term nutritional deficiencies can suffer permanent effects, including severe dementia.

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Other research suggests that cannabis may have medicinal effects for a number of gastrointestinal disorders, such as irritable bowel syndrome, whereas other research suggests that it may be associated with these types of disorders in some individuals. Simply treating the medical issue and continuing to engage in the substance abuse will not resolve the issue. For example, individuals with severe nutritional deficiencies or extensive damage to the liver may suffer the ramifications of these conditions for the remainder of their lives even if they remain drug-free.

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